PEARL Intervention to Reduce Depression Among Adults With Epilepsy

Status unconfirmed · Not applicable

Conditions studied: Depression, Epilepsy

In brief

The purpose of this study is to test the effectiveness of a home-based depression treatment intervention called "Program to Encourage Active, Rewarding Lives (PEARL)". We hypothesize that over a 12-month period, compared to usual care, those receiving the PEARL intervention will show more improvement with their depression, have higher quality of life and function, and use fewer medical services.

Key facts

Study ID

NCT00459329

Run by

University of Washington

People needed

80

Starts

2007-03-01

Expected to finish

2009-03-01

Last updated by the study team

2008-06-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Home address within 30 miles of Seattle
• Diagnosis of epilepsy (ICD-9 code 345.XX)
• Appointment in the UW REC or Neurology clinic in the past 2 years and currently enrolled in this clinic.
• Current age older than 18 years
• Diagnosis of major depression, minor depression or dysthymia
• Ability to speak/read English

You may not qualify if…

• Alcohol and/or substance abuse/dependence based on a score greater than 1 on 4-item validated CAGE-AID
• Cognitive impairment based on a score less than 3 on a 6-item validated cognitive screen
• Diagnosis of bipolar disorder, schizophrenia/schizoaffective disorder or other psychotic disorder
• Women who are pregnant or nursing
• Terminal medical illness
• Those currently seeing or planning to see a psychiatrist
• Those with suicidal ideation nearly every day

Where it is running

• Regional Epilepsy Center, Harborview Medical Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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