Efficacy and Tolerability of Switching to Ziprasidone From Other Antipsychotics

Completed · Phase 4

Conditions studied: Schizophrenia, Schizoaffective Disorder

In brief

Because ziprasidone has not been extensively studied and is not widely accepted in the severely mentally ill in State hospitals this study aims to demonstrate its effectiveness and relative lack of side effects. 75 patients with schizophrenia or schizoaffective disorder who need a change of medication because of ineffectiveness or side effects will be changed to ziprasidone and followed with detailed assessments for eight weeks. The hypothesis is that they will improve and have fewer side effects.

Key facts

Study ID

NCT00458211

Run by

Bronx Psychiatric Center

People needed

40

Starts

2005-05-01

Expected to finish

2008-04-01

Last updated by the study team

2020-05-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Schizophrenia or schizoaffective
• Capacity to give consent
• Stable, on the same medication for a month but only partial response or with unacceptable side effects 18-65 years of age

You may not qualify if…

• Repeated non-compliance
• Current depot medication
• Active medical conditions
• QTc >500msec
• Previous non-response
• Previous treatment with ziprasidone

Where it is running

• Buffalo Psychiatric Center — Buffalo, New York, United States
• Bronx Psychiatric Center — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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