A Single-Blind Trial of Risperidone vs. Paroxetine for Treatment of Panic Attacks

Completed · Not applicable

Conditions studied: Major Depression With Panic Attacks, Panic Disorder

In brief

This study compares the efficacy of risperidone to that of paroxetine in the treatment of panic attacks in patients with Panic Disorder and with Major Depressive Disorder with Panic attacks and compares the side effect profile of risperidone vs. paroxetine in treatment of panic attacks and compares response rates of risperidone vs. paroxetine in treatment of panic attacks.

Key facts

Study ID

NCT00457106

Run by

Beth Israel Medical Center

People needed

90

Starts

2002-06-01

Expected to finish

2003-06-01

Last updated by the study team

2010-12-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females, ages 18-55.
• Ability to sign an informed consent
• Diagnosis of Panic Disorder, or MDD with Panic attacks, single episode, recurrent, or chronic
• HAM-A score >17

You may not qualify if…

• Alcohol or substance abuse within the last 6 months
• Current diagnosis of Obsessive-Compulsive Disorder
• Current diagnosis of Schizophrenia, Schizoaffective Disorder, or Bipolar Mood Disorder
• Use of antipsychotic medications over the two months preceding enrollment in the study
• Changes in antidepressant or mood stabilizer dosing over the two months preceding enrollment in the study
• Previous adverse reaction to risperidone or paroxetine.

Where it is running

• Beth Israel Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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