A Comparison Between Glargine and Detemir Insulin in Type 2 Diabetes

Completed · Not applicable

Conditions studied: Type 2 Diabetes

In brief

The purpose of this study that when studies using our method of dosing adjustments driven by continuous glucose monitoring and because of the less variable glycemic effect of insulin detemir, insulin detemir treated subjects will spend a significantly greater time in the glucose target range than insulin glargine.

Key facts

Study ID

NCT00457093

Run by

Diabetes Care Center

People needed

35

Starts

2006-10-01

Expected to finish

2007-05-01

Last updated by the study team

2010-11-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Type 2 Diabetes
• Currently on a basal insulin, that is, NPH, glargine or detemir
• Capable of self monitoring glucose >4/day
• Previously complaint with clinical recommendations
• Subject may be on oral antiglycemic medications but no change in treatment is permitted during study.

You may not qualify if…

• Hb A1c >9.0%
• Urinary ketosis
• Currently or expected alteration in insulin sensitivity such as major surgery, infection, renal failure (creatine >1.5 mg/dL) glucocorticoid treatment, recent (within 2 weeks) serious hypoglycaemic episode (requires assistance of another)
• Currently participating in another clinical trial
• Known or suspected allergy to insulin glargine or detemir
• Using other insulins, such as, bolus insulin or premixed insulin
• Sight or hearing impaired
• Pregnancy oor nursing of the intention of becoming pregnant or not using adequate contraceptive measures.

Where it is running

• Diabetes Care Center — Salinas, California, United States

Full record on ClinicalTrials.gov

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