GI Reflux in Lung Transplant and Its Relationship to Chronic Rejection

Completed

Conditions studied: Gastroesophageal Reflux

In brief

Recent data has suggested that GER (gastric reflux) may worsen after lung transplantation and potentially increase the risk of chronic rejection (CR) after lung transplantation. The purpose of this study is to look at how often GER occurs in the lung transplant population and examine how GER may change the immune system and cause CR. In this way, we would be able to better identify patients that may benefit from anti-reflux procedures.

Key facts

Study ID

NCT00455078

Run by

University of Chicago

People needed

20

Starts

2007-06-01

Expected to finish

2010-01-01

Last updated by the study team

2013-09-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who are undergoing pre-lung transplant evaluations at the University of Chicago Hospital
• Patients who are capable of becoming pregnant must have a negative pregnancy test prior to consent.
• All patients must be able to give written informed consent.

You may not qualify if…

• Pre-transplant patients in whom study procedures are contraindicated or patients who are unable to complete all the study procedures.
• Patients who are unable to give consent

Where it is running

• The University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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