Treatment of Oral Warts in HIV+ Patients

Completed · Phase 2 · Has a placebo group

Conditions studied: Papillomatosis, HIV Infections

In brief

This is a study to test lozenges of interferon-alpha that are dissolved in the mouth as a treatment of oral warts in HIV-positive adults. The hypothesis of this study is that interferon-alpha will be safe and that a higher percentage of subjects given interferon-alpha will experience a complete or nearly complete remission of their oral warts compared to subjects given placebo.

Key facts

Study ID

NCT00454181

Run by

Ainos, Inc. (f/k/a Amarillo Biosciences Inc.

People needed

59

Starts

2007-02-01

Expected to finish

2009-10-01

Last updated by the study team

2011-09-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Must have tested positive for HIV.
• Must have two or more warts inside the mouth.
• Must be receiving a standard course of anti-retroviral therapy (HAART).

You may not qualify if…

• Must not be receiving oral or injected steroids.
• Must not be taking other drugs for treatment of oral warts.
• Must not have other active HIV-related opportunistic infections.

Where it is running

• University of California, School of Dentistry — San Francisco, California, United States
• Nova Southeastern University College of Dental Medicine — Fort Lauderdale, Florida, United States
• Medical College of Georgia School of Dentistry — Augusta, Georgia, United States
• University of Illinois at Chicago, College of Dentistry — Chicago, Illinois, United States
• University of Kentucky College of Dentistry — Lexington, Kentucky, United States
• University of Maryland Baltimore Dental School — Baltimore, Maryland, United States
• Division of Oral Medicine and Dentistry, Brigham and Women's Hospital — Boston, Massachusetts, United States
• UMDNJ - New Jersey Dental School — Newark, New Jersey, United States
• New York University College of Dentistry — New York, New York, United States
• University of Pennsylvania School of Dental Medicine — Philadelphia, Pennsylvania, United States
• Baylor College of Dentistry — Dallas, Texas, United States
• University of Texas Health Science Center at San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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