Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia in Remission
Status unconfirmed · Phase 3 · Has a placebo group
Conditions studied: Leukemia
In brief
RATIONALE: Vaccines made from a peptide may help the body build an effective immune response to kill cancer cells. Colony-stimulating factors, such as GM-CSF, increase the number of white blood cells and platelets found in bone marrow or peripheral blood. Giving vaccine therapy together with GM-CSF may be an effective treatment for acute myeloid leukemia. It is not yet known whether giving vaccine therapy together with GM-CSF is more effective than giving placebo together with GM-CSF in treating acute myeloid leukemia. PURPOSE: This randomized phase III trial is studying vaccine therapy and GM-CSF to see how well they work compared with a placebo and GM-CSF in treating patients with acute myeloid leukemia in remission.
Key facts
- Study ID
- NCT00454168
- Run by
- The Vaccine Company
- People needed
- 244
- Starts
- 2005-05-01
- Last updated by the study team
- 2014-01-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
- Vaccine Company — South San Francisco, California, United States
- Rush Cancer Institute at Rush University Medical Center — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
- St. Francis Hospital Cancer Care Services — Indianapolis, Indiana, United States
- Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
- Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
- Case Comprehensive Cancer Center — Cleveland, Ohio, United States
- UPMC Cancer Centers — Pittsburgh, Pennsylvania, United States
- Hollings Cancer Center at Medical University of South Carolina — Charleston, South Carolina, United States
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
- Cancer Care Centers of South Texas - Southeast — San Antonio, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.