In-exsufflator Cough Assist Device in Patients With Symptomatic Bronchiectasis

Stopped early · Not applicable

Conditions studied: Bronchiectasis

In brief

This study is a randomized, controlled trial examining the effectiveness of the mechanical cough-assist device (in-exsufflator) in promoting the clearance of retained airway secretions in patients with symptomatic bronchiectasis. We hypothesize that this enhanced clearance of airway secretions will lead to a decline in the number of acute exacerbations of bronchiectasis experienced by these patients during the study period, improve health-related quality of life, decrease overall health-care costs and improve pulmonary function.

Key facts

Study ID

NCT00452114

Run by

University of Massachusetts, Worcester

People needed

28

Starts

2004-04-01

Expected to finish

2008-05-01

Last updated by the study team

2018-09-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chest CT scan confirmation of bronchiectasis
• At least two exacerbations in the preceding 12 months requiring antibiotics

You may not qualify if…

• Cystic fibrosis
• Bullous emphysema
• History of spontaneous pneumothorax
• History of massive hemoptysis: greater than 200 cc in a 24 hour period
• Lung resection surgery in the past 6 months
• Use of the mechanical cough in-exsufflator in the prior 3 months
• Inability to speak and read English
• Inability to demonstrate proper use of the cough-assist or flutter device
• Unable to provide informed consent

Where it is running

• UMass Memorial Medical Center, Universty Campus — Worcester, Massachusetts, United States
• St. Vincent Medical Center — Worcester, Massachusetts, United States

Full record on ClinicalTrials.gov

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