Early Indicators of Chronic Rejection in Lung Transplant

Stopped early

Conditions studied: Chronic Rejection in Lung Transplant, Cytokine Production in Bos Post Lung Transplant

In brief

The purpose of this research is to discover the different patterns of cytokine production in patients who may develop Bronchiolitis Obliterans Syndrome-0p (BOS-0p) which means ongoing rejection. This is an early indicator of chronic rejection in lung transplant recipients. These cytokines can be detected in the bronchoalveolar (lung) and tissue samples of lung transplant recipients.

Key facts

Study ID

NCT00449332

Run by

University of Chicago

People needed

120

Starts

2006-03-01

Expected to finish

2013-12-01

Last updated by the study team

2016-09-20

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Lung transplant recipients between the ages of 18 and 65 years old
• All patients must be able to give written informed consent

You may not qualify if…

• Lung transplant recipients who are unable to undergo bronchoscopy
• Lung transplant recipients who are unable to give informed consent

Where it is running

• The University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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