Biobank For MS And Other Demyelinating Diseases

Running, not enrolling

Conditions studied: Multiple Sclerosis, Transverse Myelitis, Neuromyelitis Optica, Acute Disseminated Encephalomyelitis, Optic Neuritis

In brief

To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.

Key facts

Study ID

NCT00445367

Run by

Accelerated Cure Project for Multiple Sclerosis

People needed

3226

Starts

2006-05-01

Expected to finish

2036-10-01

Last updated by the study team

2025-10-02

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent
• willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture
• experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON

You may not qualify if…

• history of blood borne pathogens
• allogeneic bone marrow transplant
• clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON).
• weight less than 37 pounds

Where it is running

• Barrow Neurological Institute — Phoenix, Arizona, United States
• Stanford University — Stanford, California, United States
• The Rocky Mountain MS Center at Anschutz Medical Campus at UC Denver — Aurora, Colorado, United States
• Shepherd Center — Atlanta, Georgia, United States
• Johns Hopkins — Baltimore, Maryland, United States
• Beth Israel Deaconess — Boston, Massachusetts, United States
• University of Massachusetts Medical School — Worcester, Massachusetts, United States
• Multiple Sclerosis Research Center of New York — New York, New York, United States
• The Ohio State University — Columbus, Ohio, United States
• University of Texas Southwestern Medical Center at Dallas — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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