Laser-Ranibizumab-Triamcinolone for Proliferative Diabetic Retinopathy
Completed · Phase 3 · Has a placebo group
Conditions studied: Proliferative Diabetic Retinopathy, Diabetic Macular Edema
In brief
The purpose of the study is to find out if treatment with an intravitreal injection of triamcinolone or an intravitreal injection of ranibizumab can prevent loss of vision caused by panretinal photocoagulation treatment. At the present time, it is not known whether intravitreal steroid or anti-vascular endothelial growth factor (anti-VEGF) injections are beneficial in preventing vision loss after panretinal photocoagulation (PRP) treatment. It is possible that one or both of the types of injections will prevent vision loss after PRP treatment. However, it is not known whether the benefits of the injections will outweigh the risks. It is possible that because of side effects, the injections may not be as good as laser alone in treating the diabetic retinopathy.
Key facts
- Study ID
- NCT00445003
- Run by
- Jaeb Center for Health Research
- People needed
- 333
- Starts
- 2007-03-01
- Expected to finish
- 2010-07-01
- Last updated by the study team
- 2016-08-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Retina-Vitreous Associates Medical Group — Beverly Hills, California, United States
- University of California, Irvine — Irvine, California, United States
- Loma Linda University Health Care, Dept. of Ophthalmology — Loma Linda, California, United States
- Southern California Desert Retina Consultants, MC — Palm Springs, California, United States
- California Retina Consultants — Santa Barbara, California, United States
- Bay Area Retina Associates — Walnut Creek, California, United States
- Eldorado Retina Associates, P.C. — Louisville, Colorado, United States
- Retina Vitreous Consultants — Fort Lauderdale, Florida, United States
- Retina Consultants of Southwest Florida — Fort Myers, Florida, United States
- Central Florida Retina Institute — Lakeland, Florida, United States
- Southeast Retina Center, P.C. — Augusta, Georgia, United States
- University of Illinois at Chicago Medical Center — Chicago, Illinois, United States
- Illinois Retina Associates — Joliet, Illinois, United States
- Raj K. Maturi, M.D., P.C. — Indianapolis, Indiana, United States
- John-Kenyon American Eye Institute — New Albany, Indiana, United States
- Medical Associates Clinic, P.C. — Dubuque, Iowa, United States
- Paducah Retinal Center — Paducah, Kentucky, United States
- Maine Vitreoretinal Consultants — Bangor, Maine, United States
- Elman Retina Group, P.A. — Baltimore, Maryland, United States
- Wilmer Ophthalmological Institute at Johns Hopkins — Baltimore, Maryland, United States
- Retina Consultants of Delmarva, P.A. — Salisbury, Maryland, United States
- Ophthalmic Consultants of Boston — Boston, Massachusetts, United States
- Joslin Diabetes Center — Boston, Massachusetts, United States
- Retina Center, PA — Minneapolis, Minnesota, United States
- Sall Research Medical Center — Artesia, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.