N-Terminal Pro-brain Natriuretic Peptide Hormone and Persistent Pulmonary Hypertension

Stopped early

Conditions studied: Persistent Pulmonary Hypertension of Newborn

In brief

Babies who are suspected of having persistent pulmonary hypertension (PPHN) will be included in this study. PPHN is a condition in which the blood is restricted from flowing to the lungs in a normal way making it hard for babies to breath and placing strain on the heart. This study will observe whether certain hormones that measure stress (N-terminal pro-brain natriuretic peptide) can help determine how well a baby will do when they have PPHN.

Key facts

Study ID

NCT00443859

Run by

Christiana Care Health Services

People needed

10

Starts

2007-02-01

Expected to finish

2008-09-01

Last updated by the study team

2016-07-11

Who can join

Age: any, up to 1. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• >/= 34 weeks gestation at birth
• clinical diagnosis of PPHN

You may not qualify if…

• newborns with evidence of structural heart disease, congenital anomalies and prior use of inhaled nitric oxide.

Where it is running

• Christiana Hospital — Newark, Delaware, United States
• Thomas Jefferson University — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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