"The Evaluation of Stimulant Withdrawal"

Withdrawn before enrolling · Phase 2

Conditions studied: Anxiety, Relapse, Substance Addiction

In brief

The purpose of this research study is to determine whether Carvedilol, an FDA approved beta blocker, when administered for an 8-week period to veterans currently undergoing treatment for methamphetamine dependence (1) improves their ability to stay in treatment longer, (2)eases the aversive symptoms that accompany stimulant withdrawal, and (3) increases the time they remain abstinent from methamphetamine.

Key facts

Study ID

NCT00442923

Run by

Aaron J. Janowsky

People needed

0

Starts

2007-07-01

Expected to finish

2011-06-30

Last updated by the study team

2019-01-31

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must have entered treatment into the outpatient Clinical Addiction Rehabilitation Section (CARS) through the US Portland Veterans Affairs Medical Center
• Must meet the clinical definition for methamphetamine dependence
• Self-reported methamphetamine use within 10 days of entering the study
• Must be able to understand and sign the consent form

You may not qualify if…

• Dependent on any other drug except nicotine, caffeine, marijuana and alcohol
• Pregnant or nursing mothers
• Psychosis
• Dementia
• Any serious medical condition that could be aggravated by the study protocol (Allergic reaction, Hypotension, Asthma, Bronchospastic conditions, Angina, Bronchitis, Emphysema, Bradycardia, Heart or blood vessel disease, Diabetes mellitus, Low blood sugar, Kidney disease, Liver disease or Overactive thyroid)
• History of withdrawal seizures or delirium tremors
• Use of MAO inhibitors within the last two weeks
• Considerable hepatocellular injury, including cirrhosis of the liver or liver function test levels higher than 2 times normal

Where it is running

• US Veterans Hospital — Portland, Oregon, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.