Study On Lidocaine Vs. Placebo Pain Control During Transrectal Ultrasound Guided Prostate Biopsy

Completed · Not applicable

Conditions studied: Prostate Cancer

In brief

Patients at risk for having prostate cancer usually undergo a biopsy of their prostate. This is most often done in the private urology office. Recent studies have suggested that injection of local anesthesia (lidocaine) near the nerves of the prostate will improve pain sensation during the biopsy procedure. Local anesthesia can be given through a separate needle through the rectal probe just prior to biopsy. However, many urologists to date perform their biopsies without anesthesia. Some claim that the needle used for anesthesia causes pain itself. Others claim that the pain is so minimal that the additional use of lidocaine (and extra time) is not necessary. We plan to reexamine the use of lidocaine and perform the first study where each patient will receive lidocaine and placebo on separate sides of their prostate.

Key facts

Study ID

NCT00441532

Run by

Corewell Health East

People needed

50

Starts

2005-08-01

Expected to finish

2006-08-01

Last updated by the study team

2011-11-23

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Patients who are undergoing prostate ultrasound-guided biopsy from the practice of Drs. Diokno and Hollander.
• Patients must speak English.
• Patients must sign consent form.

You may not qualify if…

• Patients having received prior radiation to the pelvic area.
• Patients with any neurologic disorder that may interfere with pain sensation during biopsy.
• Allergy to Lidocaine
• Patients requiring additional anesthesia (e.g. anxiolytics)

Where it is running

• William Beaumont Hospital — Royal Oak, Michigan, United States

Full record on ClinicalTrials.gov

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