Bortezomib, Cyclophosphamide, Dexamethasone, and Thalidomide in Treating Patients With Newly Diagnosed, Previously Untreated Multiple Myeloma
Status unconfirmed · Phase 2
Conditions studied: Multiple Myeloma and Plasma Cell Neoplasm
In brief
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cyclophosphamide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Thalidomide may stop the growth of cancer cells by blocking blood flow to the cancer. Giving bortezomib together with cyclophosphamide, dexamethasone, and thalidomide may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving bortezomib together with cyclophosphamide, dexamethasone, and thalidomide works in treating patients with newly diagnosed, previously untreated multiple myeloma.
Key facts
- Study ID
- NCT00438841
- Run by
- Fred Hutchinson Cancer Center
- People needed
- 43
- Starts
- 2006-08-01
- Last updated by the study team
- 2009-03-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California, United States
- Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center — Los Angeles, California, United States
- Desert Regional Medical Center Comprehensive Cancer Center — Palm Springs, California, United States
- Sutter Cancer Center — Sacramento, California, United States
- Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus — Boca Raton, Florida, United States
- St. Vincent's Comprehensive Cancer Center - Manhattan — New York, New York, United States
- Oregon Health and Science University Cancer Institute — Portland, Oregon, United States
- Lone Star Oncology - Austin — Austin, Texas, United States
- Seattle Cancer Care Alliance — Seattle, Washington, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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