Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders
Completed · Phase 1
Conditions studied: Substance-Related Disorders, Depressive Disorder, Anxiety Disorder
In brief
Adolescent substance abuse results in significant negative outcomes and extraordinary costs for youths, their families, communities, and society. Moreover, rates of psychiatric comorbidity among substance abusing youth range from 25% up to 82%, and youths with a dual diagnosis have worse outcomes and are more than twice as costly to treat than their counterparts with no comorbidity. This project was a pilot test of a new treatment, OPTION-A, which was adapted from Multisystemic Therapist (MST) and other evidence-based interventions to specifically treat youth presenting for outpatient treatment of comorbid substance use and internalizing disorders. The project was a randomized controlled pilot trial comparing the experimental treatment to usual services in the community.
Key facts
- Study ID
- NCT00438685
- Run by
- Medical University of South Carolina
- People needed
- 40
- Starts
- 2004-10-01
- Expected to finish
- 2010-09-01
- Last updated by the study team
- 2018-06-14
Who can join
Age: 12 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Presentation for outpatient treatment
- 12 to 17 years of age
- Youth residing with at least one adult caregiver who serves as a parent figure
- Substance Abuse or Dependence Disorder
- Axis I Internalizing Disorder (Mood Disorder or Anxiety Disorder), based on the Diagnostic Interview Schedule for Children (DISC-IV; Shaffer, Fisher, Lucas, Dulcan, \& Schwab-Stone, 2000)
You may not qualify if…
- Pervasive Developmental Disorder
- Psychotic Disorder
- Severe or profound mental retardation (IQ of 45 or below)
- Families previously receiving Multisystemic Therapy
Where it is running
- Medical University of South Carolina, Department of Psychiatry & Behavioral Sciences, Family Services Research Center — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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