Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

Completed · Not applicable

Conditions studied: Healthy

In brief

The primary objectives of the proposed experimental and modeling efforts are to quantify the influences of acute sleep deprivation (short-term homeostatic), chronic sleep restriction (long-term homeostatic), circadian rhythmicity, and their interactions on neurocognitive performance and to develop a new model of sleep homeostasis that can predict the effects of chronic sleep restriction. This model will be based on the underlying neuroanatomy and neurophysiology. This new model will facilitate optimization of human performance in operational settings, such as are seen in military operation and other work environments.

Key facts

Study ID

NCT00438438

Run by

Brigham and Women's Hospital

People needed

9

Starts

2006-04-01

Expected to finish

2008-11-01

Last updated by the study team

2011-09-02

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-35 years old
• Medically healthy

You may not qualify if…

• Sleep disorder
• Psychiatric illness
• Chronic medical condition
• No prescription or Non-prescription medications

Where it is running

• Brigham and Woman's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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