Influence of Fitness on Brain and Cognition
Completed
Conditions studied: Aging, Cognitive Ability, General
In brief
The purpose of this study is to examine the effect of aerobic fitness training on human cognition, brain structure, and brain function of older adults.
Key facts
- Study ID
- NCT00438347
- Run by
- University of Illinois at Urbana-Champaign
- People needed
- 179
- Starts
- 2006-04-01
- Expected to finish
- 2012-05-01
- Last updated by the study team
- 2016-11-08
Who can join
Age: 60 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 60 to 75 years of age (for Sedentary Older Adults)
- Sedentary Older Adults: no physical activity in last six months; Young Comparison Sample: Moderately active lifestyle
- Capable of performing exercise
- Personal physician's examination and consent to participate in testing and exercise or control intervention
- Successful completion of graded exercise test without evidence of cardiac abnormalities or responses
- Adequate performance on the Pfeiffer (1979) Mental Status measure - Corrected (near and far) vision 20/40 or better
- Right-handed
- Intention to remain in the local area over the study period
You may not qualify if…
- Sedentary Older Adults: self reported physical activity on regular basis (2 times or more per week) in last six months; Young Comparison Sample: sedentary or highly active/athletic lifestyle
- Any physical disability that prohibits mobility (walking), stretching etc.
- Depression score on GDS indicative of clinical depression
- Presence of any implanted devices such as cardiac pacemakers or autodefibrillators; neural pacemakers, aneurysm clips in the CNS; cochlear implants; metallic bodies in the eye or CNS; any form of wires or metal devices that concentrate radiofrequency fields
- Left-handed
- Individuals with chronic inflammation (e.g. severe arthritis, psoriasis, inflammatory bowel disease, asthma, polyneuropathies, Lupus)
- Intent to move or take an extended vacation (i.e. longer than 1 month during the study period)
Where it is running
- Beckman Institute, University of Illinois — Champaign, Illinois, United States
- University of Illinois — Urbana, Illinois, United States
Full record on ClinicalTrials.gov
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