Effect of Bosentan on Exercise Capacity at High Altitude

Completed · Phase 1

Conditions studied: Altitude, Pulmonary Hypertension

In brief

This study is to determine whether bosentan will alter exercise capacity after rapid ascent to high altitude. We hypothesize that bosentan administration will improve arterial oxygenation and exercise capacity.

Key facts

Study ID

NCT00432978

Run by

VA Loma Linda Health Care System

People needed

20

Starts

2006-07-01

Expected to finish

2007-02-01

Last updated by the study team

2007-04-18

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Normal healthy subjects aged 18 - 55 years

You may not qualify if…

• Pregnancy
• Heart, lung or liver disease
• Use of glyburide, cyclosporin A

Where it is running

• VA Loma Linda Healthcare System — Loma Linda, California, United States

Full record on ClinicalTrials.gov

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