Detoxification and Treatment of Subjects With Medication Overuse Headache

Status unconfirmed · Phase 4

Conditions studied: Analgesic Rebound Headache

In brief

The purpose of this study is to assess the benefits of almotriptan used as a transitional therapy and topiramate in subjects with medication overuse headaches (MOH.

Key facts

Study ID

NCT00432549

Run by

The New England Center for Headache, P.C.

People needed

60

Starts

2007-01-01

Expected to finish

2007-02-01

Last updated by the study team

2007-02-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Medication overuse headaches 18 years of age and older Must have a diagnosis of probable medication overuse headache Must have greater than fifteen headache days per month Must be in generally good health Female subjects must be postmenopausal or practicing an acceptable method of birth control

You may not qualify if…

• Not overusing six or more tablets per day of compounds containing barbituates opioids No overuse of triptans Previous failure or side effects with topiramate or almotriptan Cannot be pregnant or lactating

Where it is running

• The New England Center for Headache, P.C. — Stamford, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

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