The PACE-MI Registry Study - Outcomes of Beta-blocker Therapy After Myocardial Infarction (OBTAIN)

Completed

Conditions studied: Myocardial Infarction

In brief

The purpose of the PACE-MI (OBTAIN) registry is: * Analyze beta-blocker dose response effect on outcome over two years * Explore gender and minority differences in beta-blocker utilization and outcomes. In patients with Myocardial Infarction (MI) discharged from the hospital, beta-blocker dose will be predictive of survival. Exploratory analyses: Gender and racial effects-gender and race are, similarly, hypothesized to be predictive of post-MI survival. The existence of interactions between gender and beta-blocker effect as well as race and beta-blocker effect will also be evaluated.

Key facts

Study ID

NCT00430612

Run by

Northwestern University

People needed

7057

Starts

2009-05-01

Expected to finish

2015-10-01

Last updated by the study team

2023-04-24

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Consecutive patients admitted with a myocardial infarction documented by both of the following:
• cardiac enzymes (CPK elevation > two times or troponin elevation > three times the upper limit of normal for the lab)
• Electrocardiographic changes and/or symptoms consistent with myocardial infarction (i.e. chest pain, shortness of breath)
• No Exclusion Criteria

Where it is running

• Little Rock Cardiology Clinic — Little Rock, Arkansas, United States
• MemorialCare Heart and Vascular Institute - Long Beach Memorial Medical Center — Long Beach, California, United States
• West Los Angeles VA Medical Center — Los Angeles, California, United States
• Bridgeport Hospital — Bridgeport, Connecticut, United States
• Baptist Cardiac and Vascular Institute — Miami, Florida, United States
• Orlando Regional Medical Center — Orlando, Florida, United States
• Northwestern Memorial Hospital — Chicago, Illinois, United States
• Clarian Health/Methodist Research Institute — Indianapolis, Indiana, United States
• Henry Ford Hospital — Detroit, Michigan, United States
• Park Nicollet — Saint Louis Park, Minnesota, United States
• Winthrop University Hospital — Bethpage, New York, United States
• Maimonides Medical Center — Brooklyn, New York, United States
• Strong Memorial Hospital (University of Rochester School of Medicine) — Rochester, New York, United States
• OhioHealth Research Institute — Columbus, Ohio, United States
• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
• Rhode Island Hospital — Providence, Rhode Island, United States
• Baptist Memorial Hospital — Memphis, Tennessee, United States
• Amarillo Heart Clinic Research Institute, Inc. — Amarillo, Texas, United States
• Austin Heart PLLC — Austin, Texas, United States
• Providence Health Center — Waco, Texas, United States
• Fletcher Allen Health Care — Burlington, Vermont, United States
• University of Calgary — Calgary, Alberta, Canada

Full record on ClinicalTrials.gov

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