Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation

Completed · Phase 1

Conditions studied: Chronic Lymphocytic Leukemia

In brief

The purpose of this research study is to collect, freeze and store leukemia cells from the blood or bone marrow of patients that have advanced chronic lymphocytic leukemia (CLL) that is not in clinical remission. This study is a companion study to DF/HCC clinical trial 06-196 in which the participants' own CLL cells may form part of a vaccine treatment for their leukemia.

Key facts

Study ID

NCT00428233

Run by

Dana-Farber Cancer Institute

People needed

65

Starts

2006-11-01

Expected to finish

2014-06-01

Last updated by the study team

2020-04-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ability to harvest CLL cells from peripheral blood, lymph nodes or bone marrow, defined as > 30% involvement of bone marrow intratrabecular space, or peripheral blood lymphocytosis > 5000/microliter, or surgically accessible lymph nodes of greater than or equal to 2cm.
• ECOG performance status 0-2
• 18 years of age or older

You may not qualify if…

• Uncontrolled infection
• Leukemia with active CNS involvement

Where it is running

• Dana-Farber Cancer Institute — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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