Glycemic Stability of Insulin Aspart Versus Insulin Lispro in Insulin Pump Therapy
Stopped early · Not applicable
Conditions studied: Type 1 Diabetes Mellitus
In brief
The purpose of this study is to determine: 1. whether there is a difference between insulin aspart and insulin lispro in continuous insulin pump therapy 2. whether duration of the insulin infusion set placement effect blood sugar control if the infusion set is in place for longer then 72-96 hours
Key facts
- Study ID
- NCT00428207
- Run by
- Joslin Diabetes Center
- People needed
- 4
- Starts
- 2007-02-01
- Expected to finish
- 2008-08-01
- Last updated by the study team
- 2017-05-30
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Type 1 diabetes treated with CSII at least 3 months.
- Males and females, > 18 years but < 75 years old.
- Hemoglobin A1c ≤ 8.0 % at measurement taken at week 0 (screening visit).
- Duration of diabetes ≥ 12 months.
- Willingness to perform self-blood glucose monitoring several times/day.
You may not qualify if…
- Previous insulin precipitation in pump infusion catheters.
- Daily insulin requirements > 25% of pump reservoir capacity. (This would preclude the subject from using the pump infusion system for more than 3 days).
- Use of an insulin pump that does not have a downloadable record of basal and bolus doses.
- Known or suspected allergy to trial products.
- Pregnancy, breast-feeding, intention to become pregnant or inadequate contraception measures.
- Known or suspected alcohol or drug abuse.
- Impaired renal function with creatinine ≥ 1.7 mg/dl.
- Pronounced catheter site scarring.
- Chronic use of drugs that may influence glycemic control (e.g. steroids).
- Any other significant concomitant disease that would interfere with participation in and completion of the trial.
Where it is running
- Joslin Diabetes Center — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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