A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)

Completed · Phase 2 · Has a placebo group

Conditions studied: Vitrectomy

In brief

A multicenter study to compare multiple doses of intravitreal microplasmin in patients undergoing surgical vitrectomy.

Key facts

Study ID

NCT00412958

Run by

ThromboGenics

People needed

125

Starts

2006-12-01

Expected to finish

2008-10-01

Last updated by the study team

2014-12-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients in whom vitrectomy is indicated

You may not qualify if…

• Posterior Vitreous Detachment (PVD) present at baseline
• Vitreous hemorrhage
• Certain vitreoretinal conditions including proliferative disease, rhegmatogenous retinal detachment, and proliferative vitreoretinopathy (PVR)
• Have had a vitrectomy in the study eye at any time

Where it is running

• Retina Centers, P.C. — Tucson, Arizona, United States
• VMR Institute — Huntington Beach, California, United States
• Jules Stein Eye Institute/UCLA — Los Angeles, California, United States
• Retinal Consultants of San Diego — Poway, California, United States
• Retinal Consultants Medical Group — Sacramento, California, United States
• National Ophtlamic Research Institute — Fort Meyers, Florida, United States
• Center for Retina and Macular Disease — Winter Haven, Florida, United States
• Rush University Med. Ctr — Chicago, Illinois, United States
• Mailing add: New England Eye Center - Tufts — Boston, Massachusetts, United States
• Associated Retinal Consultants, P.C. — Royal Oak, Michigan, United States
• Vitroretinal Surgery, PA — Minneapolis, Minnesota, United States
• Retina Vitreous Centre, PA — New Brunswick, New Jersey, United States
• Columbia University - Harkness Eye Institute — New York, New York, United States
• Retina Vitreous Surgeons of Central NY — New York, New York, United States
• Duke Eye Center — Durham, North Carolina, United States
• Retina Association of Cleveland — Lakewood, Ohio, United States
• Allegheny Ophthalmic & Orbital Associates, P.C. — Pittsburgh, Pennsylvania, United States
• Vanderbilt Eye Institute — Nashville, Tennessee, United States
• Vitreoretinal Consultants — Houston, Texas, United States
• Valley Retina Institute, P.A. — McAllen, Texas, United States

Full record on ClinicalTrials.gov

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