Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

Completed · Phase 3 · Has a placebo group

Conditions studied: Cytomegalovirus Infections

In brief

The purpose of this research study is to investigate whether or not maribavir is safe and effective for preventing CMV disease when taken by mouth for up to 12 weeks in patients who have had a stem cell transplant.

Key facts

Study ID

NCT00411645

Run by

Shire

People needed

681

Starts

2006-12-13

Expected to finish

2009-05-23

Last updated by the study team

2021-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Allogeneic stem cell transplant recipient
• Recipient or donor CMV seropositive
• Have transplant engraftment
• Able to swallow tablets

You may not qualify if…

• CMV organ disease
• HIV infection
• Use of other anti-CMV therapy post-transplant

Where it is running

• City of Hope Medical Center — Duarte, California, United States
• Scripps Green Hospital — La Jolla, California, United States
• UCSD Moores Center — La Jolla, California, United States
• UCLA Medical Center — Los Angeles, California, United States
• University of California, San Francisco — San Francisco, California, United States
• Stanford University Medical Center — Stanford, California, United States
• Rocky Mountain Cancer Center — Denver, Colorado, United States
• Shands Hospital — Gainesville, Florida, United States
• H. Lee Moffitt Cancer Center — Tampa, Florida, United States
• Emory University — Atlanta, Georgia, United States
• Northwestern University Medical Center — Chicago, Illinois, United States
• University of Chicago — Chicago, Illinois, United States
• Loyola University — Maywood, Illinois, United States
• St Francis Hospital — Beech Grove, Indiana, United States
• University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
• University of Kentucky Chandler Medical Center — Lexington, Kentucky, United States
• University Medical Center University of Louisville Hospital — Louisville, Kentucky, United States
• Greenbaum Cancer Center — Baltimore, Maryland, United States
• Massachusettes General — Boston, Massachusetts, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• University of Michigan — Ann Arbor, Michigan, United States
• Wayne State Medical Center — Detroit, Michigan, United States
• Henry Ford Health System — Detroit, Michigan, United States
• University of Arkansas Myeloma Institute — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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