A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury

Completed · Phase 3 · Has a placebo group

Conditions studied: Neuralgia, Spinal Cord Injuries

In brief

The purpose of this study is to evaluate if pregabalin relieves nerve pain associated with spinal cord injury compared to placebo (pill that contains no active medicine). This study will also evaluate the safety of pregabalin in this patient population.

Key facts

Study ID

NCT00407745

Run by

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

People needed

220

Starts

2007-01-01

Expected to finish

2011-02-01

Last updated by the study team

2021-01-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with nerve pain after Spinal cord injury (traumatic, diving, ischemic and after removal of benign tumors (except meningioma and fibromas)
• Pain has to be chronic(continuous for at least 3 months or intermittent for at least 6 months
• Pain score at least 4 in 4 of 7 days prior to receive treatment.

You may not qualify if…

• Pregabalin use in the last 60 days, prior intolerance to pregabalin
• Creatinine clearance <60 mL/min.
• White blood cell count <2500/mm3; neutrophil count <1500/mm3; platelet count <100 x 103/ mm3.
• Abuse of drugs or alcohol
• Unstable medial conditions
• Clinically significant abnormal electrocardiogram (ECG).
• Presence of severe pain associated with conditions other than spinal cord injury that could confound the assessment or self-evaluation of pain due to spinal cord injury.

Where it is running

• Pfizer Investigational Site — Phoenix, Arizona, United States
• Pfizer Investigational Site — Phoenix, Arizona, United States
• Pfizer Investigational Site — Fresno, California, United States
• Pfizer Investigational Site — Napa, California, United States
• Pfizer Investigational Site — Northridge, California, United States
• Pfizer Investigational Site — Pasadena, California, United States
• Pfizer Investigational Site — Miami, Florida, United States
• Pfizer Investigational Site — Miami, Florida, United States
• Pfizer Investigational Site — Orlando, Florida, United States
• Pfizer Investigational Site — Indianapolis, Indiana, United States
• Pfizer Investigational Site — Overland Park, Kansas, United States
• Pfizer Investigational Site — Detroit, Michigan, United States
• Pfizer Investigational Site — New York, New York, United States
• Pfizer Investigational Site — White Plains, New York, United States
• Pfizer Investigational Site — Winston-Salem, North Carolina, United States
• Pfizer Investigational Site — Bellevue, Ohio, United States
• Pfizer Investigational Site — Johnstown, Pennsylvania, United States
• Pfizer Investigational Site — Philadelphia, Pennsylvania, United States
• Pfizer Investigational Site — Dallas, Texas, United States
• Pfizer Investigational Site — Charleston, West Virginia, United States
• Pfizer Investigational Site — Charleston, West Virginia, United States
• Pfizer Investigational Site — Viña del Mar, Valparaiso, Chile
• Pfizer Investigational Site — Beijing, Beijing Municipality, China
• Pfizer Investigational Site — Chengdu, Sichuan, China
• Pfizer Investigational Site — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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