The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years

Completed

Conditions studied: Upper Respiratory Infection, Common Cold

In brief

This study examines the cold processes of children aged 6 to less than 14. Children will be seen by the study staff 6 days in a row during the course of their naturally-acquired colds. Nasal secretions will be examined for chemicals that the body creates during a cold. Skin cells will be collected by brushing the inside of the child's cheek with a small brush. The cells will be examined for genes that may hold control the creation of these chemicals.

Key facts

Study ID

NCT00405509

Run by

West Penn Allegheny Health System

People needed

33

Starts

2006-10-01

Expected to finish

2009-01-01

Last updated by the study team

2016-08-19

Who can join

Age: 6 and older, up to 13. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children 6 to < 14 years of age.
• Common cold symptoms for less than 24 hours.
• At least 2 of the following 8 symptoms: cough, headache, hoarseness, muscle ache, nasal drainage, nasal congestion, scratchy throat, and sneezing.

You may not qualify if…

• Investigational medication in past 30 days.
• History of persistent asthma or other chronic diseases.
• Patients with nasal ulcers within the past 1 month, nasal surgery within the past 6 months, nasal trauma within the past 2 months or presence of nasal polyps or nasal deformities causing significant nasal obstruction.
• Patients with evidence of significant nasal septal deviation.
• Patients with a positive rapid antigen test for streptococcal infection.
• Common cold symptoms for more than 24 hours.

Where it is running

• Allegheny General Hospital — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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