Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat

Completed · Phase 3 · Has a placebo group

Conditions studied: Pharyngitis

In brief

We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind, placebo-controlled conditions.

Key facts

Study ID

NCT00402987

Run by

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

People needed

269

Starts

2006-12-04

Expected to finish

2007-11-15

Last updated by the study team

2021-03-03

Who can join

Age: 18 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The patient must have a diagnosis of pharyngitis with objective findings of tonsillo-pharyngitis.
• The patient is willing to take "nothing by mouth" including inhaled treatments except trial medication during the two hours while at the site and following trial drug administration (e.g. not smoking, food, drink, candy, lozenges, chewing gum). The patient will be allowed food and drink between hours 2 and 24, but no other oral or inhaled treatments such as smoking, lozenges, chewing gum. After the two hour assessment, the patients will be allowed food and drink within one half-hour following any hourly evaluations sore throat.

You may not qualify if…

• The patient has used any analgesic/antipyretic within 1 dosing interval preceding administration of the first dose of trial medication.
• The patient anticipates using any inhaled therapy including beta-agonists (e.g., ventolin) during the 24 hour trial period and, if used, has only used inhaled therapy on an intermittent basis in the week prior to the screening visit.

Where it is running

• University of Connecticut Student Health Services — Storrs, Connecticut, United States

Full record on ClinicalTrials.gov

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