Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
Completed · Not applicable · Has a placebo group
Conditions studied: Glaucoma, Ocular Hypertension
In brief
The Purpose of This Study is to Determine if Taking an Over the Counter Non-Steroidal Anti-Inflammatory(Ibuprofen)has an Effect on Eye Pressure in Patients using Brimonidine(Alphagan)and Latanoprost(Xalatan) eye drops.
Key facts
- Study ID
- NCT00402493
- Run by
- Philadelphia Eye Associates
- People needed
- 51
- Starts
- 2006-12-01
- Expected to finish
- 2008-03-01
- Last updated by the study team
- 2018-04-04
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with bilateral or unilateral primary open angle glaucoma or ocular hypertension
- An IOP in each eye of greater than 22mm HG after washout of IOP lowering medications
- No worse than 20/200 best corrected visual acuity
- Normal appearing or non-occludable anterior chamber angles
- Discontinuation of current POAG or OH medications before participation in the study.
- Written Informed Consent
You may not qualify if…
- Use of any other ocular medications
- Previous ocular surgery or laser therapy within the last three months.
- Systemic treatment with any adrenergic agonist or antagonist, corticosteroid or nonsteroidal anti-inflammatory agents(low dose apsirin will be accepted if dose remains the same for entire study period).
- An age of less than 21,of child bearing age and currently pregnant, considering pregnancy or a nursing mother.
- A history of medical noncompliance or unreliability.
- Presence of uncontrolled hypertension, cardiac arrhythmia, cerebrovascular accident, nasal polyps, bleeding diathesis, peptic ulcer disease, gastritis or known intolerance, contraindication or allergy to any drugs used in the study.
- Lactose Intolerance.
Where it is running
- Philadelphia Eye Associates — Willingboro, New Jersey, United States
- Philadelphia Eye Associates — Philadelphia, Pennsylvania, United States
- Philadelphia Eye Associates — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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