Transfusion-Associated Microchimerism in Individuals Receiving a Blood Transfusion After a Traumatic Injury

Completed

Conditions studied: Chimerism, Blood Transfusion, Wounds and Injuries

In brief

Individuals who experience a traumatic injury often have a significant amount of blood loss and may require a blood transfusion. In some individuals who receive a blood transfusion, white blood cells from the donor's blood may remain in the body for years, a condition known as microchimerism. This study will examine the reasons why microchimerism occurs in some blood transfusion recipients and not others.

Key facts

Study ID

NCT00400192

Run by

Vitalant Research Institute

People needed

451

Starts

2006-11-01

Expected to finish

2012-07-01

Last updated by the study team

2013-04-15

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Hospitalized for a traumatic injury
• Received at least one unit of transfused red blood cells

You may not qualify if…

• Currently incarcerated
• Inadequate decision-making capacity of the participant and no available surrogate decision-maker
• Prior bone marrow or solid organ transplantation

Where it is running

• University of California, Davis, Medical Center — Sacramento, California, United States

Full record on ClinicalTrials.gov

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