Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation

Completed · Phase 2

Conditions studied: Ventilator Associated Pneumonia, Respiratory Infection, Tracheobronchitis

In brief

The purpose of this study was to determine the effect of aerosolized antibiotics on respiratory infection in mechanically ventilated patients.We hypothesize that aerosolized antibiotics , which achieve high drug concentrations in the airway, would more effectively treat respiratory infection, decrease the need for systemic antibiotics and decrease antibiotic resistance.

Key facts

Study ID

NCT00396578

Run by

Stony Brook University

People needed

80

Starts

2003-08-01

Expected to finish

2004-09-01

Last updated by the study team

2006-11-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• be on mechanical ventilation greater than 3 days
• greater than or equal to 18 years of age survival greater than 14 days
• greater than 2 ccs of tracheal secretions/4 hours

You may not qualify if…

• allergy to drugs, pregnancy

Where it is running

• University Hospital Medical Center — Stony Brook, New York, United States

Full record on ClinicalTrials.gov

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