Development of Serologic Assays for Human Herpes Virus-8

Completed

Conditions studied: Kaposi Sarcoma, HIV Infection

In brief

Dr. Burbelo and colleagues have developed a technique for rapidly and quantitatively detecting antibody responses in sera to a variety of pathogens using recombinant proteins. We would like to apply this technique to develop an assay for detecting antibodies to HHV-8 (KSHV, the etiologic agents of Kaposi's sarcoma, an AIDS-defining condition). We initially plan to examine samples from patients with Kaposi's sarcoma, since all those patients are almost certainly infected with HHV-8. We are thus using samples from patients with previously diagnosed Kaposi's sarcoma. The samples in question are stored at the NCI FCRF repository operated by SAIC Frederick or in Rockville, MD.

Key facts

Study ID
NCT00395278
Run by
National Institutes of Health Clinical Center (CC)
People needed
394
Starts
2006-10-30
Expected to finish
2020-12-10
Last updated by the study team
2020-12-11

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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