Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

Completed

Conditions studied: Asthma

In brief

Asthma is one of the most common childhood diseases. It is chronic and often severely disabling. The amount of nitric oxide that is exhaled while breathing increases with airway inflammation, a symptom of asthma. This study will examine the results from a previous study, the Cincinnati Asthma Prevention (CAP) study, to evaluate the effects of environmental and genetic factors on exhaled nitric oxide (eNO) levels and to determine the relationship between eNO and asthma severity.

Key facts

Study ID

NCT00395096

Run by

Children's Hospital Medical Center, Cincinnati

People needed

225

Starts

2006-07-01

Expected to finish

2008-06-01

Last updated by the study team

2021-08-09

Who can join

Age: 6 and older, up to 12. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participated in the Cincinnati Asthma Prevention Study
• Diagnosis of asthma
• Lives with someone that smokes at least 5 cigarettes a day

You may not qualify if…

• No additional neuromuscular or respiratory disorder that may interfere with safe participation in the parent study
• Does not have electricity
• Plans to move within 1 year of entry into the parent study

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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