Chemoradiation-Induced Nausea and Emesis: Quality of Life

Stopped early

Conditions studied: Gastric Cancer, Pancreatic Cancer, Cervical Cancer, Vulvar Cancer, Endometrial Cancer, Anal Cancer

In brief

The primary objectives of this study are: 1. To assess the preferences of cancer patients scheduled to receive chemoradiation and caregiver controls for side-effects of chemoradiation. 1. To compare preferences of cancer patients to those of healthy individuals. 2. To compare how patients' preferences for side-effects of chemoradiation change over time. 2. To longitudinally assess the quality of life of cancer patients scheduled to receive chemoradiation. 3. To determine the impact of nausea and vomiting associated with chemoradiation on patients' quality of life and evaluate potential change throughout the duration of chemoradiation treatment.

Key facts

Study ID

NCT00394602

Run by

M.D. Anderson Cancer Center

People needed

207

Starts

2004-04-07

Expected to finish

2019-05-08

Last updated by the study team

2020-01-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients receiving 5 to 6-week course of chemoradiation for abdominal-pelvic tumors (gastric cancers, gastro-esophageal (GE) junction, pancreatic, cervix, vulvar, endometrial, or anal) using conventional fractionation [(180cGy-200cGy per day)]
• Patients receiving concurrent abdominal-pelvic radiation and single agent or combination of cisplatin, paclitaxel, CPT-11, oxaliplatin or 5-FU, capecitabine, gemcitabine, or bevacizumab (Avastin).
• Patients must be least 18 years of age
• Controls must be individuals with no prior cancer diagnosis
• Controls must be at least 18 years of age
• Controls must be the caregivers of patients on this study

You may not qualify if…

• Patients who do not have a diagnosis of cervix, endometrial, vulvar or anal cancer
• Patients who are not scheduled to receive chemoradiation treatment
• Patients who are not at least 18 years of age
• Controls - individuals who have a prior diagnosis of cancer (with the exception of non-melanoma skin cancer)
• Controls - individuals who are not at least 18 years of age

Where it is running

• University of Texas MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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