Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving rituximab together with combination chemotherapy may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving rituximab together with combination chemotherapy works in treating patients with newly diagnosed, HIV-associated Burkitt's lymphoma.
Key facts
- Study ID
- NCT00392834
- Run by
- AIDS Malignancy Consortium
- People needed
- 34
- Starts
- 2006-09-01
- Expected to finish
- 2013-07-01
- Last updated by the study team
- 2018-06-06
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- UCLA Clinical AIDS Research and Education (CARE) Center — Los Angeles, California, United States
- UCSF Medical Center at Parnassus — San Francisco, California, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
- Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis, Missouri, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- Albert Einstein Cancer Center at Albert Einstein College of Medicine — The Bronx, New York, United States
- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
- Pennsylvania Oncology Hematology Associates, Incorporated - Philadelphia — Philadelphia, Pennsylvania, United States
- Floyd and Delores Jones Cancer Institute at Virginia Mason Medical Center — Seattle, Washington, United States
- West Virginia University Health Sciences Center - Charleston — Charleston, West Virginia, United States
Full record on ClinicalTrials.gov
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