Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)

Completed · Phase 2

Conditions studied: Chronic Constipation

In brief

Study 0038 compares the safety and effectiveness of an investigational drug, TD-5108 with placebo (a sugar pill) for the treatment of chronic constipation.

Key facts

Study ID

NCT00391820

Run by

Alfasigma S.p.A.

People needed

360

Starts

2006-10-01

Expected to finish

2007-05-01

Last updated by the study team

2025-07-08

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meet ROME III Criteria

You may not qualify if…

• Constipation caused by:colonic etiology, pelvic floor dysfunction, metabolic disturbances, neurologic disturbances,concomitant medications affecting bowel function
• Chronic treatment with anticholinergics, narcotic analgesics
• Irritable Bowel Syndrome

Where it is running

• Breco Research — Houston, Texas, United States

Full record on ClinicalTrials.gov

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