Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed AIDS-Related B-Cell Non-Hodgkin's Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some find cancer cells and help kill them or carry cancer-killing substances to them. Others interfere with the ability of cancer cells to grow and spread. Giving combination chemotherapy together with rituximab may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with rituximab works in treating patients with newly diagnosed AIDS-related B-cell non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00389818
- Run by
- AIDS Malignancy Consortium
- People needed
- 43
- Starts
- 2007-01-01
- Expected to finish
- 2011-09-01
- Last updated by the study team
- 2018-06-06
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- UCLA Clinical AIDS Research and Education (CARE) Center — Los Angeles, California, United States
- University of Miami Sylvester Comprehensive Cancer Center - Miami — Miami, Florida, United States
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago, Illinois, United States
- Ochsner Cancer Institute at Ochsner Clinic Foundation — New Orleans, Louisiana, United States
- Boston University Cancer Research Center — Boston, Massachusetts, United States
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
- Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis, Missouri, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- Albert Einstein Cancer Center at Albert Einstein College of Medicine — The Bronx, New York, United States
- Case Comprehensive Cancer Center — Cleveland, Ohio, United States
- Joan Karnell Cancer Center at Pennsylvania Hospital — Philadelphia, Pennsylvania, United States
- Virginia Mason Medical Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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