Efficacy and Safety Study of an Antiarrhythmic Drug to Treat Atrial Fibrillation in Patients With Pacemakers

Completed · Phase 2 · Has a placebo group

Conditions studied: Atrial Fibrillation

In brief

The purpose of this study is to determine the safety and efficacy of an investigational antiarrhythmic drug (ATI-2042) in the treatment of atrial fibrillation in patients with a dual chamber pacemaker.

Key facts

Study ID

NCT00389792

Run by

ARYx Therapeutics

People needed

72

Starts

2006-07-01

Expected to finish

2008-12-01

Last updated by the study team

2009-03-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Proven paroxysmal atrial fibrillation
• Pacemaker with appropriate AF diagnostics and recording capabilities

You may not qualify if…

• Known allergy to Amiodarone or previous treatment for severe Amiodarone toxicity
• Cardioversion within one month of screening
• Severe left ventricular dysfunction or CHF with NYHA Class III or above

Where it is running

• ARYx Investigational Site — Phoenix, Arizona, United States
• ARYx Investigational Site — Scottsdale, Arizona, United States
• ARYx Investigational Site — Tucson, Arizona, United States
• ARYx Investigational Site — Larkspur, California, United States
• ARYx Investigational Site — Aurora, Colorado, United States
• ARYx Investigational Site — Hollywood, Florida, United States
• ARYx Investigational Site — Jacksonville Beach, Florida, United States
• ARYx Investigational Site — Atlanta, Georgia, United States
• ARYx Investigational Site — Marietta, Georgia, United States
• ARYx Investigational Site — Chicago, Illinois, United States
• ARYx Investigational Site — Towson, Maryland, United States
• ARYx Investigational Site — Saginaw, Michigan, United States
• ARYx Investigational Site — Minneapolis, Minnesota, United States
• ARYx Investigational Site — St Louis, Missouri, United States
• ARYx Investigational Site — Lincoln, Nebraska, United States
• ARYx Investigational Site — Warren Township, New Jersey, United States
• ARYx Investigational Site — Albuquerque, New Mexico, United States
• ARYx Investigational Site — Buffalo, New York, United States
• ARYx Investigational Site — Hershey, Pennsylvania, United States
• ARYx Investigational Site — Wynnewood, Pennsylvania, United States
• ARYx Investigational Site — Charleston, South Carolina, United States
• ARYx Investigational Site — Nashville, Tennessee, United States
• ARYx Investigational Site — Austin, Texas, United States
• ARYx Investigational Site — Houston, Texas, United States
• ARYx Investigational Site — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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