Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder

Completed · Not applicable · Has a placebo group

Conditions studied: Obsessive-Compulsive Disorder

In brief

This study will compare the short- and long-term effectiveness of two common therapies in improving serotonin reuptake inhibitor treatment in people with obsessive-compulsive disorder.

Key facts

Study ID

NCT00389493

Run by

New York State Psychiatric Institute

People needed

100

Starts

2006-10-01

Expected to finish

2012-12-01

Last updated by the study team

2014-04-25

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Primary diagnosis of OCD
• Currently on a stable and adequate dose of an SRI
• Sufficient severity of symptoms to warrant additional augmentation treatment

You may not qualify if…

• Medical or psychiatric conditions that would make participation in the study unsafe
• Currently receiving psychotherapy elsewhere at the time of study entry
• Previously (within 12 weeks prior to study entry) attended 8 or more sessions of EX/RP within a 2-month period or received at least 4 weeks of antipsychotic augmentation while on an adequate SRI dose
• Currently being treated with an SRI for the first time and has not yet responded, but has not tried another SRI

Where it is running

• New York State Psychiatric Institute — New York, New York, United States
• University of Pennsylvania Center for the Treatment and Study of Anxiety — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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