Efficacy and Safety Study of Seroquel SR in the Treatment of Major Depressive Disorder

Completed · Phase 3

Conditions studied: Major Depressive Disorder

In brief

The primary purpose of this study is to evaluate whether treatment with (SEROQUEL SR) quetiapine fumarate sustained release (SR) for 9 weeks compared to placebo will improve depressive symptoms in elderly patients with major depressive disorder. PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.

Key facts

Study ID

NCT00388973

Run by

AstraZeneca

People needed

338

Starts

2006-09-01

Expected to finish

2007-12-01

Last updated by the study team

2010-04-01

Who can join

Age: 66 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female patients, 66 years or older, with a documented clinical diagnosis of MDD.

You may not qualify if…

• The presence of dementia or mental disorder other than MDD within 6 months of enrolment,
• Uncontrolled hypertension, substance or alcohol abuse
• A current diagnosis of cancer or a current or past diagnosis of stroke

Where it is running

• Research Site — Birmingham, Alabama, United States
• Research Site — San Diego, California, United States
• Research Site — Fort Myers, Florida, United States
• Research Site — Gainsville, Florida, United States
• Research Site — Sarasota, Florida, United States
• Research Site — Roswell, Georgia, United States
• Research Site — Boston, Massachusetts, United States
• Research Site — Brooklyn, New York, United States
• Research Site — Eugene, Oregon, United States
• Research Site — Jenkintown, Pennsylvania, United States
• Research Site — Memphis, Tennessee, United States
• Research Site — Austin, Texas, United States
• Research Site — San Antonio, Texas, United States
• Research Site — City Bell, Buenos Aires, Argentina
• Research Site — La Plata, Buenos Aires, Argentina
• Research Site — Córdoba, Córdoba Province, Argentina
• Research Site — Mendoza, Mendoza Province, Argentina
• Research Site — Buenos Aires, Argentina
• Research Site — Capital Federal, Argentina
• Research Site — Tartu, Estonia, Estonia
• Research Site — Tallinn, Estonia
• Research Site — Viljandi, Estonia
• Research Site — Helsinki, Finland, Finland
• Research Site — Tampere, Finland, Finland
• Research Site — Jarvenpaa, Finland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.