Radiofrequency Ablation in Treating Patients With Early Invasive Breast Cancer or Ductal Carcinoma in Situ
Completed · Not applicable
Conditions studied: Breast Cancer
In brief
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. Giving radiofrequency ablation before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This clinical trial is studying how well radiofrequency ablation followed by surgery works in treating patients with early invasive breast cancer or ductal carcinoma in situ.
Key facts
- Study ID
- NCT00388115
- Run by
- University of California, Davis
- People needed
- 15
- Starts
- 2001-10-01
- Expected to finish
- 2007-05-01
- Last updated by the study team
- 2010-03-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Females of ages ≥18 years.
- Core biopsy proven invasive breast cancer OR
- Core biopsy proven low or intermediate grade DCIS.
- Tumor less than or equal to 2.0 cm in diameter.
- No prior surgical treatment for breast cancer within 30 days.
- Life expectancy of > 10 years, not including the diagnosis of cancer.
- ECOG performance status of 0-2.
- Informed consent given.
- Multifocal invasive breast cancer patients are eligible. All tumors that are palpable or visualized by USS can be treated.
You may not qualify if…
- Male subjects.
- Ages < 18 years.
- Breast tumor > 2.0 cm in diameter.
- Evidence of distant metastatic disease.
- Evidence of diffuse calcification suggestive of extensive or multifocal DCIS.
- High grade DCIS or presence of comedo-necrosis because these lesions can be associated with invasive breast cancer, which would go undetected if the lesion is entirely destroyed by the RF ablation.
Where it is running
- University of California Davis Cancer Center — Sacramento, California, United States
Full record on ClinicalTrials.gov
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