Bortezomib and Topotecan in Treating Patients With Advanced Solid Tumors
Completed · Phase 1
Conditions studied: Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
In brief
RATIONALE: Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bortezomib together with topotecan may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of bortezomib and topotecan in treating patients with advanced solid tumors.
Key facts
- Study ID
- NCT00388089
- Run by
- University of California, Davis
- People needed
- 24
- Starts
- 2004-12-01
- Expected to finish
- 2008-06-01
- Last updated by the study team
- 2010-06-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California Davis Cancer Center — Sacramento, California, United States
Full record on ClinicalTrials.gov
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