Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
Completed · Phase 1/Phase 2 · Has a placebo group
Conditions studied: Congestive Heart Failure
In brief
In congestive heart failure, cardiac output is low, blood pressure is high, and the body becomes congested with fluid. In normal people, when there is high blood pressure, the heart muscle cells secrete a hormone that excretes sodium and water in the urine, reducing blood pressure. The action of this hormone is called the natriuretic response. The purpose of this study is to determine if nesiritide can improve an impaired natriuretic response in subjects with asymptomatic systolic heart failure or asymptomatic diastolic heart failure.
Key facts
- Study ID
- NCT00387621
- Run by
- Horng Chen
- People needed
- 58
- Starts
- 2006-02-01
- Expected to finish
- 2009-08-01
- Last updated by the study team
- 2012-05-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.