Phase II Study of Dasatinib (BMS-354825) for Androgen-deprived Progressive Prostate Cancer

Completed · Phase 2

Conditions studied: Prostate Cancer

In brief

The purpose of this study is to learn if men with metastatic prostate cancer and rising Prostate Specific Antigen (PSA), who have been surgically castrated or are undergoing androgen deprivation with Luteinizing Hormone Releasing Hormone (LHRH) treatment, respond to dasatinib. The safety of this treatment will also be studied.

Key facts

Study ID

NCT00385580

Run by

Bristol-Myers Squibb

People needed

94

Starts

2007-01-01

Expected to finish

2010-10-01

Last updated by the study team

2013-04-30

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• males, 18 or older
• proven advanced prostate cancer
• documented metastatic disease
• rising PSA levels
• castrate levels of testosterone

You may not qualify if…

• symptomatic CNS (brain or spinal cord) metastasis
• medical condition which may increase the risk of toxicity
• any prior or ongoing anti-cancer medical therapy or immunotherapy for prostate cancer other than primary androgen deprivation agents
• unable to take oral medication

Where it is running

• Cedars Sinai Medical Center — Los Angeles, California, United States
• University Of Chicago — Chicago, Illinois, United States
• The Bunting Blaustein Cancer Research Building — Baltimore, Maryland, United States
• Memorial Sloan-Kettering Cancer Center-Sidney Kimmel Center — New York, New York, United States
• Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States
• Seattle Cancer Care Alliance — Seattle, Washington, United States
• University Of Wisconsin Paul P Carbone Comprehensive Ca Ctr — Madison, Wisconsin, United States
• Local Institution — Montpellier, France
• Local Institution — Paris, France
• Local Institution — Villejuif, France
• Local Institution — Rome, Italy

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.