A Study of rhBMP-2/CPM in Closed Fractures of the Humerus

Completed · Phase 2

Conditions studied: Fractures

In brief

The primary objective of this study is to assess whether fracture union is accelerated in subjects with humeral fractures (proximal,diaphyseal) treated with conservative therapy (standard of care) and a single dose of rhBMP-2/CPM compared to subjects who receive standard of care alone.

Key facts

Study ID

NCT00384852

Run by

Wyeth is now a wholly owned subsidiary of Pfizer

People needed

139

Starts

2007-01-01

Expected to finish

2010-02-01

Last updated by the study team

2013-02-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Skeletally mature subjects age 18 years or older.
• Subjects with either a closed proximal humeral fracture or a diaphyseal humeral fracture.
• Treatment plan that includes only conservative (nonoperative) therapy within 48 hours following injury.

You may not qualify if…

• Shoulder dislocation at the time of injury.
• Planned procedure(s) at that would stimulate fracture union at the time of application of the initial immobilization device.
• Fractures located in the distal third of humerus.

Where it is running

• Study site — Little Rock, Arkansas, United States
• Study site — Aurora, Colorado, United States
• Study site — Denver, Colorado, United States
• Study site — Clearwater, Florida, United States
• Study site — St. Petersburg, Florida, United States
• Study site — Brooklyn, New York, United States
• Study site — Monroe, North Carolina, United States
• Study site — Toledo, Ohio, United States
• Study site — State College, Pennsylvania, United States
• Study site — Herston, Queensland, Australia
• Study site — Adelaide, South Australia, Australia
• Study site — Melbourne, Victoria, Australia
• Study site — São Paulo, São Paulo, Brazil
• Study site — São Paulo, São Paulo, Brazil
• Study site — Vancouver, British Columbia, Canada
• Study site — Ajax, Ontario, Canada
• Study site — Chatham, Ontario, Canada
• Study site — Oshawa, Ontario, Canada
• Study site — Scarborough Village, Ontario, Canada
• Study site — Windsor, Ontario, Canada
• Study site — Montreal, Quebec, Canada
• Study site — Charlottetown, Canada
• Study site — Oulu, Finland
• Study site — Turku, Finland
• Study site — Angers, France

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.