Mifepristone and Mid-Trimester Termination of Pregnancy

Completed · Not applicable

Conditions studied: Abortion, Induced, Abortion, Second Trimester

In brief

Mid-second trimester medical terminations of pregnancy require admission to the hospital for the length of time it takes a woman to abort. The current protocol at BMC uses intra-amniotic digoxin injection the day prior to admission. The following day, the woman is admitted and given sequential doses of misoprostol until delivery occurs. The average length of time between the first dose of misoprostol and delivery is 12 hours, requiring most women to stay overnight. This is a randomized, placebo-controlled, double-blinded study designed to determine whether adding mifepristone significantly reduces the induction interval time (time between starting the first misoprostol and delivery) required for a second trimester termination.

Key facts

Study ID

NCT00382538

Run by

Boston University

People needed

64

Starts

2005-03-01

Expected to finish

2006-11-01

Last updated by the study team

2008-10-07

Who can join

Age: 16 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 16 years of age or over
• able to give informed consent in English or Spanish
• Requesting termination of pregnancy

You may not qualify if…

• Under 16 years of age
• rupture membranes or intrauterine death

Where it is running

• Boston Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.