Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer
Status unconfirmed · Phase 3 · Has a placebo group
Conditions studied: Breast Cancer
In brief
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. It is not yet known whether letrozole is more effective than a placebo in treating patients with hormone receptor-positive breast cancer. PURPOSE: This randomized phase III trial is studying letrozole to see how well it works compared with a placebo in treating postmenopausal women who have received hormone therapy for hormone receptor-positive breast cancer.
Key facts
- Study ID
- NCT00382070
- Run by
- NSABP Foundation Inc
- People needed
- 3966
- Starts
- 2006-08-01
- Expected to finish
- 2025-04-01
- Last updated by the study team
- 2024-03-22
Who can join
Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Connecticut Oncology & Hematology - Torrington — Torrington, Connecticut, United States
- Harold Leever Regional Cancer Center — Waterbury, Connecticut, United States
- Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center — Grand Junction, Colorado, United States
- North Colorado Medical Center — Greeley, Colorado, United States
- Sky Ridge Medical Center — Lone Tree, Colorado, United States
- Hope Cancer Care Center at Longmont United Hospital — Longmont, Colorado, United States
- McKee Medical Center — Loveland, Colorado, United States
- St. Mary - Corwin Regional Medical Center — Pueblo, Colorado, United States
- North Suburban Medical Center — Thornton, Colorado, United States
- Exempla Lutheran Medical Center — Wheat Ridge, Colorado, United States
- Bridgeport Hospital — Bridgeport, Connecticut, United States
- Bristol Hospital — Bristol, Connecticut, United States
- Praxair Cancer Center at Danbury Hospital — Danbury, Connecticut, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center — Farmington, Connecticut, United States
- Helen and Harry Gray Cancer Center at Hartford Hospital — Hartford, Connecticut, United States
- Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center — Hartford, Connecticut, United States
- Middlesex Hospital Cancer Center — Middletown, Connecticut, United States
- Norwalk Hospital — Norwalk, Connecticut, United States
- Eastern Connecticut Hematology and Oncology Associates — Norwich, Connecticut, United States
- Carl and Dorothy Bennett Cancer Center at Stamford Hospital — Stamford, Connecticut, United States
- Pacific Shores Medical Group - Long Beach — Long Beach, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Front Range Cancer Specialists — Fort Collins, Colorado, United States
Full record on ClinicalTrials.gov
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