Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia

Completed · Phase 3

Conditions studied: Hyponatremia

In brief

This study will investigate the application of a vasopressin antagonist in the treatment of hyponatremia most likely caused by inappropriate AVP secretion. The population studied will include patients with euvolemic or hypervolemic hyponatremia.

Key facts

Study ID

NCT00380575

Run by

Cumberland Pharmaceuticals

People needed

84

Starts

2000-08-01

Expected to finish

2003-02-01

Last updated by the study team

2014-05-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Serum sodium levels 115 to < 130mEq/L
• Euvolemic or Hypervolemic hyponatremia

You may not qualify if…

• Clinical evidence of volume depletion or dehydration
• Untreated severe hypothyroidism, hyperthyroidism, or adrenal insufficiency
• Uncontrolled brady-or tachyarrhythmias requiring pacemaker placement or treatment

Where it is running

• Study site — Mobile, Alabama, United States
• Study site — Phoenix, Arizona, United States
• Study site — Tuscon, Arizona, United States
• Study site — La Jolla, California, United States
• Study site — Los Angeles, California, United States
• Study site — Santa Rosa, California, United States
• Study site — Miami, Florida, United States
• Study site — Plantation, Florida, United States
• Study site — Springfield, Illinois, United States
• Study site — Indianapolis, Indiana, United States
• Study site — Shreveport, Louisiana, United States
• Study site — Worchester, Massachusetts, United States
• Study site — Petoskey, Michigan, United States
• Study site — Minneapolis, Minnesota, United States
• Study site — Rolla, Missouri, United States
• Study site — St Louis, Missouri, United States
• Study site — Omaha, Nebraska, United States
• Study site — New York, New York, United States
• Study site — Cleveland, Ohio, United States
• Study site — Oklahoma City, Oklahoma, United States
• Study site — Columbia, South Carolina, United States
• Study site — Sioux Falls, South Dakota, United States
• Study site — Chattanooga, Tennessee, United States
• Study site — Norfolk, Virginia, United States
• Study site — Salem, Virginia, United States

Full record on ClinicalTrials.gov

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