Trabectedin in Treating Patients With Advanced, Persistent, or Recurrent Leiomyosarcoma of the Uterus

Completed · Phase 2

Conditions studied: Sarcoma

In brief

RATIONALE: Drugs used in chemotherapy, such as trabectedin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well trabectedin works in treating patients with advanced, persistent, or recurrent leiomyosarcoma of the uterus.

Key facts

Study ID

NCT00379145

Run by

Gynecologic Oncology Group

People needed

20

Starts

2007-06-01

Last updated by the study team

2017-12-12

Who can join

Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.

Where it is running

• USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
• Helen and Harry Gray Cancer Center at Hartford Hospital — Hartford, Connecticut, United States
• George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus — New Britain, Connecticut, United States
• Washington Cancer Institute at Washington Hospital Center — Washington D.C., District of Columbia, United States
• MBCCOP - Medical College of Georgia Cancer Center — Augusta, Georgia, United States
• Central Georgia Gynecologic Oncology — Macon, Georgia, United States
• Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
• Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago, Illinois, United States
• Hinsdale Hematology Oncology Associates — Hinsdale, Illinois, United States
• St. Vincent Indianapolis Hospital — Indianapolis, Indiana, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
• West Michigan Cancer Center — Kalamazoo, Michigan, United States
• St. John's Regional Health Center — Springfield, Missouri, United States
• Women's Cancer Center - Lake Mead — Las Vegas, Nevada, United States
• University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
• SUNY Downstate Medical Center — Brooklyn, New York, United States
• Memorial Sloan-Kettering Cancer Center — New York, New York, United States
• Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
• Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
• Presbyterian Cancer Center at Presbyterian Hospital — Charlotte, North Carolina, United States
• Duke Comprehensive Cancer Center — Durham, North Carolina, United States
• Case Comprehensive Cancer Center — Cleveland, Ohio, United States
• MetroHealth Cancer Care Center at MetroHealth Medical Center — Cleveland, Ohio, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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