Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Completed · Phase 3
Conditions studied: Breast Cancer, Cognitive/Functional Effects, Lung Cancer, Metastatic Cancer, Prostate Cancer
In brief
RATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether stereotactic radiation therapy is more effective with or without whole-brain radiation therapy in treating patients with brain metastases. PURPOSE: This randomized phase III trial is studying stereotactic radiation therapy and whole-brain radiation therapy to see how well they work compared with stereotactic radiation therapy alone in treating patients with brain metastases.
Key facts
- Study ID
- NCT00377156
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 213
- Starts
- 2006-07-01
- Expected to finish
- 2019-12-15
- Last updated by the study team
- 2022-09-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Arizona Oncology Services Foundation — Scottsdale, Arizona, United States
- Memorial Medical Center — Modesto, California, United States
- Kaiser Permanente - Division of Research - Oakland — Oakland, California, United States
- St. Joseph Hospital Regional Cancer Center - Orange — Orange, California, United States
- Rohnert Park Cancer Center — Rohnert Park, California, United States
- Kaiser Permanente Medical Center - Santa Clara Kiely Campus — Santa Clara, California, United States
- Kaiser Permanente Medical Center - Santa Rosa — Santa Rosa, California, United States
- University of Colorado Cancer Center at UC Health Sciences Center — Aurora, Colorado, United States
- Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
- Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
- Florida Hospital Cancer Institute at Florida Hospital Orlando — Orlando, Florida, United States
- Northside Hospital Cancer Center — Atlanta, Georgia, United States
- Saint Joseph's Hospital of Atlanta — Atlanta, Georgia, United States
- Northeast Georgia Medical Center — Gainesville, Georgia, United States
- Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler — Savannah, Georgia, United States
- Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center — Boise, Idaho, United States
- Northwest Community Hospital — Arlington Heights, Illinois, United States
- Via Christi Cancer Center at Via Christi Regional Medical Center — Wichita, Kansas, United States
- Lucille P. Markey Cancer Center at University of Kentucky — Lexington, Kentucky, United States
- Owensboro Mercy Medical Center — Owensboro, Kentucky, United States
- Ochsner Cancer Institute at Ochsner Clinic Foundation — New Orleans, Louisiana, United States
- Lowell General Hospital — Lowell, Massachusetts, United States
- Saint Vincent Hospital at Worcester Medical Center — Worcester, Massachusetts, United States
- Henry Ford Hospital — Detroit, Michigan, United States
- Arizona Oncology-Deer Valley Center — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.